- Characterised by intense itching and recurrent lesions, atopic dermatitis inflicts a substantial physical and mental burden on patients.2
- Patients with moderate to severe atopic dermatitis report potentially debilitating signs and symptoms such as excessive itch, dryness, scaling, and open sores – all of which can lead lead to sleep disturbance, pain, and impaired social functioning.3
Atopic Dermatitis Burden: Debilitating and more severe
Patients with inadequately controlled atopic dermatitis suffer greater physician-rated disease severity and physician-rated burden than those with controlled atopic dermatitis4
Correlation of atopic dermatitis disease severity with inadequate disease control
Disease burden in controlled vs inadequately controlled atopic dermatitis patients
A chronic and persistent condition, atopic dermatitis can manifest differently in each patient.5
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- Suárez-Fariñas M, Tintle SJ, Shemer A, et al. Non-lesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities. J Allergy Clin Immunol. 2011;127(4):954-964.e1-4.
- Weidinger S, Novak N. Atopic dermatitis. Lancet. 2016;387(10023):1109-1122.
- Silverberg JI, Kantor R. The role of interleukins 4 and/or 13 in the pathophysiology and treatment of atopic dermatitis. Dermatol Clin. 2017;35(3):327-334.
- Wei W, Anderson P, Gadkari A, et al. Extent and consequences of inadequate disease control among adults with a history of moderate to severe atopic dermatitis. J Dermatol. 2018;45(2):150-157.
- Silverberg JI, Gelfand JM, Margolis DJ, et al. Patient burden and quality of life in atopic dermatitis in US adults: a population-based cross-sectional study. Ann Allergy Asthma Immunol. 2018;121(3):340-347.